Cortisone Explained: Uses, Benefits, and Potential Side Effects

Cortisone is a natural substance belonging to the class of corticosteroids: cortisol (also known as hydrocortisone) and corticosterone are released into the blood by the adrenal glands together with adrenaline when we are under stress.

These steroid hormones are directly involved in the body in a wide range of physiological processes, such as the regulation of inflammation . The term “cortisone” describes all natural glucocorticoids, used as anti-inflammatories orally, through intramuscular injections or for topical use to calm the skin and mucous membranes during a flare-up.

Now that we know what it is, let’s see specifically what cortisone is used for in the treatment of certain inflammations. Cortisone is in fact a drug used in the treatment of various disorders, as an anti-inflammatory and immunosuppressant . The effect of this natural hormone is never immediate, but requires a few hours to take effect and show benefits. During an inflammatory state, cortisone is able to inhibit the formation of chemical substances that are directly responsible for the inflammatory reaction, such as prostaglandins and histamine. The dosage of intake depends on many individual factors, including the response to the drug and the severity of the condition. Cortisone treatment must always be interrupted gradually, following the instructions of the attending physician.

The main drugs on the market that contain cortisone are:

• Bentelan , Ecoval and Beben.
• Advantan .
• Decadron .
• Deltacortene .

Cortisone can be administered for allergies , collagen and ophthalmic diseases, gastrointestinal problems and dermatological conditions , including:

• Arthritis.
• Inflammation and joint pain.
• Dermatitis.
• Allergic reactions.
• Asthma.
• Rhinitis.
• Systemic lupus erythematosus.
• Hepatitis.
• Inflammatory bowel disease.
• Neoplasms.

For the skin, the properties of cortisone are widely recognized when it comes to treating the symptoms of Atopic Dermatitis because the hormone suppresses the immune system’s overreaction, relieving inflammation. Atopic Dermatitis is a  skin condition that makes it dry, red, irritable and itchy, negatively affecting the quality of life and sleep.

The use of cortisone is not recommended for a long period of time because over time it tends to thin the skin (atrophy), making it more sensitive. Especially in the case of high oral dosages, cortisone would in fact increase the risk of atrophy. Cortisone should therefore be used with caution, carefully following the dosages prescribed by the doctor.

For the daily care of Atopic Dermatitis, we recommend the Eucerin AtopiControl range for intense and long-lasting relief of atopic skin. Eucerin AtopiControl products have been proven to be gentle, provide significant results and promote a good night’s sleep, improving the quality of life.

There are several side effects of cortisone and in particular the administration of the drug is not indicated in subjects who suffer from:

• Tuberculosis.
• Ocular herpes simplex.
• Systemic fungal infections.
• Psychosis
• Intestinal anastomoses.
• Gastroduodenal ulcers.
• Renal failure.
• Osteoporosis.

Cortisone can also have side effects such as swelling, water retention, mood changes (euphoria, insomnia and depression) and cannot be prescribed to those who do sports because, without therapeutic need, it can cause a positive anti-doping test. Particular attention must also be paid when using cortisone in conjunction with other drugs so as not to compromise their effect.

Some people think that cortisone makes you hungry, is this true? In fact, you may feel an increase in the sensation of hunger, resulting in weight gain. This type of side effect can be kept under control by following a balanced diet combined with constant physical activity.

We recommend that you carefully read the list of side effects before starting a cortisone treatment to avoid allergic reactions and other disorders. In any case, consulting a doctor is always the right thing to do, especially if you are using cortisone-based preparations.

Even children may experience some contraindications after prolonged cortisone therapy. Here are the possible risks:

• weakening of the immune system;
• slowing of growth;
• recurrences of ear infections, sore throat, respiratory system disorders;
• hypertension;
• hyperglycemia.

In any case, it is essential to scrupulously follow the indications and prescriptions of a doctor and keep the child under medical supervision.